2019 Conference

 
 
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RUNX1 ASPEN 2019
3RD ANNUAL SCIENTIFIC CONFERENCE
ASPEN INSTITUTE, COLORADO, OCT 2-4, 2019

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Organizer: RUNX1 Research Program

Our third annual scientific conference will take place this fall at the renowned Aspen Institute, in Aspen, Colorado.

Recipients of our shared grant programs with Alex’s Lemonade Stand Foundation and the  Leukemia & Lymphoma Society, as well as our independent grant awardees, will be presenting the status of their research. There will also be an update on the state of the RUNX1-FPD Centralized Mutation Database.

The objectives of our scientific meetings are to learn from each other, encourage cross-pollination of ideas and data-sharing to advance our program’s research prerogatives quickly and efficiently. This spring we unveiled a new tagline: ‘One Goal. Prevent Cancer.’ Our primary goal is to forge a path towards preventing blood cancer for RUNX1-FPD patients, and eventually for all patients of hereditary blood cancer disorders.

Over the last several years we have been creating a global community of stakeholders tackling RUNX1-FPD, and this meeting offers us an invaluable opportunity to have our community of researchers come together under one roof.

Last year, there was overwhelming positive feedback on the inclusion of guest speakers who are thought leaders in clonal hematopoiesis at our Santa Barbara conference. This year we have been investigating the potential for a gene editing approach for our disorder, and are honored to have Dr. Matt Porteus of Stanford coming to speak on the advances in gene editing of hematopoietic stem cells.

Dr. Paul Liu’s ( principal investigator) NIH RUNX1-FPD Clinical Research Study is now live. His staff, Dr. Lea Cunningham, medical director, and Matt Mergueian, clinical fellow, will provide an update on the state of the study. There are many more speakers to come, and this page will be updated accordingly over the coming months.

We hope you will join us.


PROGRAM

Aspen Institute, Aspen Meadows Resort
845 Meadows Rd, Aspen, CO 81611

Wednesday, October 2

  • 17:00 – 18:00 Opening Reception

  • 18:00 – 18:10 Opening Remarks

  • 18:10 – 18:30 State of RRP

  • 18:30 – 19:30 Dinner

Session 1. New RRP Awardees and Updates on the Natural History Study and Mutation Database

  • 19:30 – 19:50 Zuzana Tothova

  • 19:50 - 19:55 Q&A

  • 19:50 – 20:10 Marc Raaijmakers

  • 20:10 - 20:15 Q&A

  • 20:15 – 20:30 Lea Cunningham/Matt Merguerian

  • 20:30 – 21:30 Dessert and Networking


Thursday, October 3

  • 7:30 – 8:30 Breakfast

  • 8:30 – 8:45 Anna Brown

  • 8:45 – 8:50 Q&A

  • 8:50 - 9:05 Mrinal Patnaik

  • 9:05 - 9:10 Q&A

Session 2. Targeting Inflammation

  • 9:10 – 9:25 Nancy Speck

  • 9:25 – 9:30 Q&A

  • 9:30 – 9:45 Coffee Break

  • 9:45 – 10:00 Anupriya Agarwal

  • 10:00 – 10:05 Q&A

  • 10:05 – 10:20 Road map towards an inflammation intervention

  • 10:20 – 11:20 Breakout session 1: critiquing road map

  • 11:20 – 11:30 Group 1 present feedback and lead discussion

  • 11:30 – 11:40 Group 2 present feedback and lead discussion

  • 11:40 – 11:50 Group 3 present feedback and lead discussion

  • 11:50 – 12:00 Group 4 present feedback and lead discussion

  • 12:00 – 13:00 Lunch

Session 3. Disease Models

  • 13:00 – 13:15 Len Zon

  • 13:15 – 13:20 Q&A

  • 13:20 – 13:35 Eirini Papapetrou

  • 13:35 – 13:40 Q&A

  • 13:40 – 13:55 Lucio Castilla

  • 13:55 – 14:00 Q&A

  • 14:00 – 14:15 Ravi Majeti

  • 14:15 – 14:20 Q&A

14:20 – 14:45 Coffee Break

Session 4. Genome Editing

  • 14:45 – 15:15 Advances in genome editing of HSPCs - Matt Porteus

  • 15:15 – 15:30 Q&A

  • 15:30 – 15:45 Paul Liu

  • 15:45 – 15:50 Q&A

  • 15:50 - 16:20 Group discussion and key takeaways for the day

  • 17:30 – 18:30 Hike/SAB meeting

  • 19:00 – 20:00 Dinner


Friday, October 4

  • 7:30 – 8:30 Breakfast

Session 5. Raising RUNX1 Activity

  • 8:30 – 8:45 Morty Poncz

  • 8:45 – 8:50 Q&A

  • 8:50 – 9:05 Alan Cantor

  • 9:05 – 9:10 Q&A

  • 9:10 – 9:25 Stephen Nimer

  • 9:25 – 9:30 Q&A

  • 9:30 - 9:45 . Coffee Break

Session 6. Targeting Multi-hit Progenitors

  • 9:45 – 10:00 Guy Sauvageau

  • 10:00 – 10:05 Q&A

  • 10:05 – 10:20 Ben Ebert lab

  • 10:20 – 10:25 Q&A

  • 10:25 – 11:00 Group Discussion on key takeaways, challenges, next steps

  • 11:00 – 11:15 Private Collection

  • 11:30 – 12:30 Lunch