“Modeling RUNX1-associated clonal hematopoietic disorders in zebrafish.” - PROJECT COMPLETED
Dr. Zon will use his ‘famous’ zebrafish program to model RUNX1-FPD to study and understand the combination of secondary mutations to understand disease pathogenesis.
This would allow for early recognition in order to reverse abnormally mutated clonal expansion and restore normal hematopoiesis.