5/6/24

Interface guided phenotyping of coding variants in the transcription factor RUNX1 with SEUSS

Dr. Hannah Carter (UCSD) discusses how she and her colleagues employed SEUSS, a Perturb-seq-like methodology, to generate and assay mutations at physical interfaces of the RUNX1 Runt domain.

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An Approach to Screening Drugs for Preventing Disease Progression in Patients with RUNX1-FPD

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RUNX1 Attenuates Toll-Like Receptor and Type I Interferon Signaling in Neutrophils